Group B Streptococcus, phospholipids and pulmonary hypertension

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Group B streptococcal phospholipid causes pulmonary hypertension.

Group B Streptococcus is the most common cause of bacterial infection in the newborn. Infection in many cases causes persistent pulmonary hypertension, which impairs gas exchange in the lung. We purified the bacterial components causing pulmonary hypertension and identified them as cardiolipin and phosphatidylglycerol. Synthetic cardiolipin or phosphatidylglycerol also induced pulmonary hyperte...

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ژورنال

عنوان ژورنال: Journal of Perinatology

سال: 2011

ISSN: 0743-8346,1476-5543

DOI: 10.1038/jp.2010.168